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And with weight gain — moderate though it was — the participant’s underlying biological profiles shifted too. The 17-member Stanford research team included experts with Stanford Bio-X, the Stanford Child Health Research Institute, the Stanford Cancer Institute, the Stanford Neurosciences Institute and the Stanford Cardiovascular Institute. Researchers at the Jackson Laboratory for Genomic Medicine and others contributed. The scientists’ analysis revealed a shift in the body’s microbiome, the vast army of microbes that protect us against germs, break down food to release energy, produce vitamins and perform other tasks. But not all of the changes were consistent across every participant.

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The Random Readers will read and discuss “The Goldfinch” by Donna Tartt, a novel that won Pulitzer Prize for Fiction. “The Goldfinch” is a mesmerizing, stay-up-all-night and tell-all-your-friends triumph, an old-fashioned story of loss and obsession, survival and self-invention, and the ruthless machinations of fate. The meeting is at 2 p.m., Wednesday, June 24, at Orinda Books, at 276 Village Square, Orinda. They meet monthly at Orinda Books and welcome new members. For more information, call 925-254-7606 or visit www.orindabooks.com.

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2. The new Mac Pro is beautiful – and on sale now. Starting today you can pre-order Apple’s new Mac Pro. The latest desktop computer from Apple stands just under 10 inches tall, is 6.6 inches in diameter and weighs in at a heavier-than-expected 11 pounds. All of the ports are located on the back side of the computer’s cylindrical design, and it stays cool with a barely perceptible fan. And it looks a lot cooler than a giant rectangle. Read more: Up close and personal with the new Mac Pro (hands-on)(The Verge).